Amedco - Quiz

May 2013 JPGN Articles


A   - 5.5%
B   - 10.5%
C   - 15.5%
D   - 20.5%

A   - Switch to an alternate anti-TNF therapy
B   - Reduce the dose of anti-TNF
C   - Continue anti-TNF therapy without further interventions.
D   - Continue anti-TNF therapy and consider dermatology referral.

A   - Guttate psoriasis
B   - Palmoplantar pustular psoriasis
C   - Inverse psoriasis

A   - This study firmly establishes that polymorphisms in the IL-23-receptor gene can accurately identify those patients at risk of developing psoriasis/psoriasiform lesions while being treated with anti-TNF-? therapy.
B   - Patients developing psoriasis in the setting of anti-TNF-? therapy were more likely to carry polymorphisms in the IL-23-receptor gene than those who did not develop psoriasis; however the study was too small to draw any firm conclusions
C   - Patients with IL-23-receptor polymorphisms who developed psoriasis were less likely to respond to topical therapy.
D   - None of the above

A   - T cell homing to the liver after priming by gut associated lymphoid tissue(GALT) derived dendritic cells may be a possible basis of extra-intestinal manifestations of chronic inflammatory bowel disease.
B   - T cells activated by liver sinusoidal endothelial cells acquire the capacity to home to intestine and the GALT.
C   - Gut-liver axis modulates the intestinal microflora, modifies the intestinal barrier function, and determines metabolic effects on near and far organs and systems.
D   - All of the above

A   - Gut microbiota alteration can induce liver insult by influencing the trafficking of molecules from the intestine into the portal circulation
B   - Gut microbiota is not influenced by breast feeding and westernized diet
C   - Gut microbiota can increase the ethanol level in the serum, so causing alcoholic liver disease

A   - Reduction in Bacteroidetes and increase in Firmicutes
B   - Breast-feeding

A   - Gut microbiota modulation may have influence on near and far organs and systems
B   - Gut microbiota modulation may be obtained through pre-, pro-, and sym-biotics
C   - Gut microbiota modulation may lead to modification of intestinal barrier function